Saturday, May 27, 2006

Birthday

Just wish me a happy birthday and move on because soon I'll be so soaked up in alcohol I may just answer inappropriately!

Thirty two and counting for the soon to be full-fledged doctor

Thursday, May 25, 2006

Electronic Medical Record (Oh Doctor...)

This week's issue of JAMA has a commentary essay about the new Electronic Medical Record system. I'd have to say that it's right on the money for how inconvinient sifting through any chart is these days. The essay is available here for free and is written in a format that really drives the point home! (highly recommended)

EMR (Electronic Medical Records) is the new standard in medical technology. Basically, hospitals are hoping to have the entire medical record of patients available on the computer system, including all notes written for that patient. You can see the potential benefits, however, the idea has run into a few obstacles:
While EMR is highly efficient in producing notes, virtually all of its notes are longer, recombinant versions of previous notes. Even notes of different authors are morphed by EMR into clones of one another. As physicians have become more adept with the time-saving features of EMR, their notes have been rendered incapable of conveying usable information by their bloated and obfuscated nature.
For one, the notes never change. The longest note I've seen thus far here was seven pages long. SEVEN pages for a daily progress note. By a Doctor!
Moreover, EMR encourages everyone to copy-and-paste the notes of everyone else so that notes become the same from author to author as well as from day to day. Even consultants are assimilated into the oneness of the EMR Borg. A cardiology consultant recently copied-and-pasted the intern's note into his own, even including "consult cardiology in AM" in his recommendations. Perhaps he meant consult a more thoughtful cardiologist.

I'm all for making the intern's job a little easier (actually, no I'm not!) but this is really starting to get ridiculous, not to mention, downright dangerous.

For example, I am aware of a case where a patient expired due to what the team thought was a Deep Vein Thrombosis that traveled to the lungs. The team was aware of the DVT and were treating it appropriately, however, the intern's notes make no mention of the possible DVT. They were continually copied and pasted. The doctors who are now being sued have very little evidence to back them with no documentation.
It should be pointed out that EMR has some laudable aspects. Notes can be created quickly with minimal cognitive effort, and their impressive length implies diligence and attention to detail.

"Minimal cognitive Effort" is the correct term here.

Tuesday, May 16, 2006

Grand Rounds

This week's Grand Rounds are held at Doc Around the Clock.

and someone's trying to put together a Pediatrics Grand Rounds.

Saturday, May 13, 2006

David Blaine is Dying to Breath

About four years ago I ran into David Blaine in a crowded New York City subway station. He was performing his usual card tricks for the local street gangs. I had admired his magic for years and really thought that, as the locals say, he “Got Skillz”. I watched for twenty minutes and then went on my way but it was the highlight of my day. There is no doubt his talent is far superior to others in his field.

Of course, if you were one of the lucky few million that caught his special the other night on ABC then you probably already know what I mean. As of late though, he’s taken to doing all sorts of ‘pseudo’ tricks, like living in a bubble full of water for one week in the middle of Lincoln Center.

“Why the hell would anyone want to live under water for one full week?” I’ll venture to say it’s good for publicity. But why am I even discussing the subject on a medical blog?

Here we are and it’s Sunday night and there is a man on television about to suffer through a live apnea test in front of the whole world! And in my twisted doctor mind part of me wished I could test his blood gases, I could peak at his pH. Maybe even figure out how he would do it. So I kinda did and I thought I would share some of what I’ve learned with you. But before I launch into that, you must be wondering what the apnea test is.

Taken literally the word “apnea” means “cessation of breathing” and the main purpose of this test is to determine if a patient is clinically brain dead. It’s used mainly when it is believed that the patient underwent such a catastrophic event that he/she no longer has any brain function, including the drive to breath. We believe that brain death is the equivalent of death and we use the apnea test, as one test among others, to confirm clinical brain death.

How is the test performed? The patient is disconnected from the ventilator for ten minutes and monitored for spontaneous breathing. At the same time, we continually monitor their blood gases (the concentration of oxygen and carbon dioxide in their blood) throughout the test. When a human being ceases to breathe the concentration of carbon dioxide in the blood rises and the concentration of oxygen falls. Patients fail the test if the concentration of carbon dioxide in the blood rise to twenty above baseline levels and no spontaneous breath is recorded. But how does all this relate to breath-holding in a live human being. Well, it technically doesn’t, but the same process will go on there as well. Slowly, the amount of oxygen in Blaine’s body will dwindle as the carbon dioxide level will rise. Slowly but surely, the feeling will become unbearable and his brain will begin to signal frantically for oxygen. But at what point will all this become so unbearable that it will override his will not to inhale?

There aren’t many studies that have investigated the human ability to breath-hold. But those that have been conducted have shown that breath-hold duration depends on numerous variables. One fact of solace was that, regardless of the circumstances, human beings seem incapable of holding their breath to unconsciousness.

For one, breath hold duration is increased by increasing lung inflation. One would expect that lung volume would stay constant during breath holding but this doesn't appear to be the case, mainly due to complicated pressure gradients that are beyond the scope of this discussion. However, one theory was that the breakpoint (point at which breath holding is no longer possible) may be dependent on some minimum chest size when this deflation would cause sufficient feedback to the brain respiratory center to initiate a breath. This however does not appear to be the case.

Interestingly, breath holding duration is almost doubled by either starting with a lower than normal blood carbon dioxide level, which can be achieved by hyperventilation or holding with gas mixtures that have an excessive concentration of oxygen. For those who witnessed the event, Blaine was coached to hyperventilate (purge) prior to going under, presumably to decrease the carbon dioxide levels in his blood. Obviously, he did his homework.

Increased metabolic rates decrease breath hold duration. Likewise, decreased metabolic rates increase it. I would suppose that it wouldn't be unreasonable to think that the tank that Blaine used was probably cooled to temperatures that would decrease metabolic demand during the final event. Surely, Blaine would have taken advantage of this phenomenon.

Do arterial chemo receptors dictate the breath breakpoint, maybe yes and maybe no. the fact that there is no consistent carbon dioxide blood level at breakpoint in study subjects suggest that this is not the case, however, one experiment in patients whose arterial chemo receptors were not functional showed that these subjects could breath-hold almost double the time of healthy subjects. I can't put it past Blaine to somehow alter the response of his chemo receptors prior to the event but I believe it is unlikely.

The bottom line:

Was I the only one who thought Evil Knievil was going to bitch slap Blaine during the interview? I bet not.

During the interview Blaine demonstrated that he could hold his breath for approximately five minutes (an amazing amount of time), or 305 seconds. if Blaine was to cool the water tank to decrease his metabolic rate and even increase his breath holding duration by 25% (no exact prolongation constant is available) than he would be able to hold his breath under these conditions for approximately 6 and one half minutes. By hyperventilating prior to starting the hold he would increase his time easily by an additional 25% which would conclude a total time of eight minutes (assuming he did not do this prior to his breath hold with kenivel).

Blaine was able to hold seven minutes and ten seconds. Pretty damn good but not much improved from his prior attempt with kenivel once all other factors are taken into account.

Overall, I think it’s safe to assume the event was more of a publicity stunt for Blaine’s magic than for actually breaking the world record. The special was good. Some of the tricks were unbelievable. Now all that’s left is to see what he’s going to do next.

Heck, he’s had a week under water to think about it!

A great article on the factors involved in breath holding can be found here.

Sunday, May 07, 2006

High-Fiving Where the Sun Don' t Shine

All three colonoscopies didn't hurt. In fact, the only thing I remember of them was the sweet dream a little versed and dilaudid can induce. The first could actually be my first anatomy class. Some previous girlfriends would beg to differ!

I was 17 years old and after years of digestive problems I finally earned a trip to where ‘the sun don’t shine’. They tried to knock me out but didn't quite get it right. Seeing the inside of my own body was, I thought, 'so cool'!

Recently, I saw a commercial on television featuring patients exiting the colonoscopy suite high fiving everyone outside. I'm not sure it quite captures the mood of relief after the experience but kudos for the public awareness campaign. I'd rather spread the word about a possible life saving colonoscopy than about the HPV test no one really needs, or the Viagra. Personally I think they should follow every Cialis commercial with one for genital herpes. But I digress.

Colon cancer is the second most common cancer in both men and women and is responsibly for nearly fifty thousand deaths per year. This year alone, 150,000 people will be diagnosed with this disease.

Although there is no study proving that colonoscopies prevent colon cancer there is a lot of indirect evidence to support this hypothesis. Early carcinomas have been found in adenomas and the distribution of the two in the colon is very similar. Guaiac stool cards have been found to decrease the rate of colon cancer, presumably because they lead to a colonoscopy.

I understand the recent popularity of virtual colonoscopy, however, from this perspective I can say it's "virtually" useless, for anything other than making the radiologists richer. The preparation for the procedure is exactly the same and at least during a colonoscopy the patient receives sedation. Furthermore, during a colonoscopy, if something is found it can be resected immediately. If a cancer or polyp is found on a virtual colonoscopy the patient will need a real colonoscopy to boot. Bottom line, from the perspective of a three time veteran of colonoscopy the prep is by far the worst part of it and it's not any more comfortable for a virtual colonoscopy.

And this is the most important reason for getting your colonoscopy. There are only a handful of cancers for which prevention is effective, the rest are either screened for (to identify those who already have the disease) or not even screened for (no effective test). A colonoscopy can not only screen but at times can actually be curative.

It seems a complete waste when a father or a grandmother dies from a CANCER that could have been cured in a matter of minutes years earlier.

So get past your homophobia and get a colonoscopy if you need one. It rarely hurts, I promise.

And take my word for it; a little Versed is a lot of fun!